Dental/ Teeth hypersensitivity and Tannic acid–iron(III) [TA/Fe3+]

Last updated: 2020-02-12  |  735 Views  | 

Dental/ Teeth hypersensitivity and Tannic acid–iron(III) [TA/Fe3+]

Dental hypersensitivity due to exposure of dentinal tubules under the enamel layer to saliva is a very popular and highly elusive technology priority in dentistry. Blocking water flow within exposed dentinal tubules is a key principle for curing dental hypersensitivity. Some salts used in “at home” solutions remineralize the tubules inside by concentrating saliva ingredients. An “in-office” option of applying dense resin sealants on the tubule entrance has only localized effects on well-defined sore spots.

Approximately 15% to 57% of adults experience dental hypersensitivity, which is a frequent and sharp dental pain, for which a specific and effective nonoperative treatment is yet to be developed. Human teeth are primarily composed of highly mineralised hydroxyapatite (HA)-containing enamel and less mineralised HA-containing dentin with 2–5-μm dentinal tubules. The pain stems from fluid flow within the exposed dentinal tubules that occurs in response to thermal, evaporative, tactile, osmotic, chemical, and electrical stimuli.

Tannic acid–iron(III) complex quickly and effectively occluded the dentinal tubules of human teeth. It withstood intense tooth brushing and induced hydroxyapatite remineralisation within the dentinal tubules. This strategy holds great promise for future applications as an effective and user-friendly desensitizer for managing dental hypersensitivity.

In addition, the TA/Fe3+ coating showed low-toxicity and good physiological affinity to the periodontal ligament, which is a tissue adjacent to dentin. The TA/Fe3+ complex-mediated coating overall is a solution for treating dentin hypersensitivity and for developing anisotropic Hydroxyapatite Crystal-HA-embedded hybrids that are applicable to emerging biomedical materials.

Ref: A rapid, efficient, and facile solution for dental hypersensitivity: The tannin–iron complex, Dongyeop X. Oh, Ekavianty Prajatelistia, Sung-Won Ju, Hyo Jeong Kim, Soo-Jin Baek, Hyung Joon Cha, Sang Ho Jun, Jin-Soo Ahn, and Dong Soo Hwang

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